Ameliorative effect of Silybum marianum extract "Milk thistle" against Lithium-induced cardiac toxicity in adult male albino rats.
نویسندگان
چکیده
منابع مشابه
Milk Thistle (Silybum marianum)
Milk thistle is a well known and commonly used herb, used particularly in hepatic diseases. It has very potent antioxidant, anti-inflammatory, and antifibrotic properties (1). As a single agent its therapeutic effects in liver disease appear to be modest (2,3,4,5). Herbal medicines and supplements are likely to be much more beneficial when used synergistically in combinations or formulas. Milk ...
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Background: Glyphosate is the most widely used herbicide, and it poses numerous health risks to the environment and living organisms. This study aimed at assessing the protective role of Adansonia digitata (A. digitata) on glyphosate-induced hepatorenal toxicity in a Wistar rat model. Methods: Twenty-five rats were randomly divided into five groups of five animals each. The first group did not...
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Nonylphenol (NP) has been considered an endocrine disrupting substance causing reproductive dysfunction and increase in reactive oxygen species production in different organs including testis. Propolis is a honeybee product that has an antioxidant property. The aim of this study was to elucidate the protective effects of propolis against reproductive toxicity induced by NP in male rats. Five ex...
متن کاملEffect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan.
PURPOSE Milk thistle (Silybum marianum) is one of the most commonly used herbal therapies, and its principal constituent silybin significantly inhibits cytochrome P450 isoform 3A4 (CYP3A4) and UDP glucuronosyltransferase isoform 1A1 (UGT1A1) in vitro. Here, we investigated whether milk thistle affects the pharmacokinetics of irinotecan, a substrate for CYP3A4 and UGT1A1, in humans. EXPERIMENT...
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ژورنال
عنوان ژورنال: Mansoura Journal of Forensic Medicine and Clinical Toxicology
سال: 2023
ISSN: ['2682-3217', '1110-5437']
DOI: https://doi.org/10.21608/mjfmct.2023.201132.1061